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In an effort to develop an effective and safe vaccine for lyme disease, rhesus macaques were injected with a multiantigenic preparation ofBorrelia burgdorferi,strain N40. One month later animals were boosted before intradermal challenge with infectiousB. burgdorferi.Challenges were performed at 1 and again at 5 months after the booster vaccination. Vaccinated and control nonvaccinated animals were...
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