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AMP-activated protein kinase (AMPK), a principal intracellular energy sensor, plays a crucial role in cell growth, proliferation, apoptosis and autophagy. Imiquimod (IMQ) directly exhibits anti-tumor activity through the induction of apoptosis and autophagic cell death.To evaluate the role of AMPK in IMQ-induced apoptosis and autophagy.The phosphorylation of AMPK and its substrates was detected by...
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