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Most patients presenting with allergies are first seen by primary care health professionals. The perceived knowledge gaps and educational needs were recently assessed in response to which the LOGOGRAM Task Force was established with the remit of constructing pragmatic flow diagrams for common allergic conditions in line with an earlier EAACI proposal to develop simplified pathways for the diagnosis...
The aim of this survey was to explore the specific educational needs of a cohort of European GPs with regards to allergy training so that future educational initiatives may better support the delivery of allergy services in primary care. Method: This study took the form of a cross‐sectional observational study in which a structured electronic questionnaire was distributed to primary care providers,...
Background
There is currently considerable uncertainty regarding what the predictors of the severity of diagnostic or accidental food allergic reactions are, and to what extent the severity of such reactions can be predicted.
Objective
To identify predictors for the severity of diagnostic and accidental food allergic reactions and to quantify their impact.
Methods
The study population consisted...
BackgroundPresently, no validated data exist on symptom severity and disease‐specific quality‐of‐life (QoL) for patients with mastocytosis. Simultaneously, clinical trials and drug application processes increasingly mandate reporting patients’ perspectives on symptoms and QoL. We report on the development and validation of the mastocytosis quality‐of‐life questionnaire (MQLQ) and the mastocytosis...
The time during which children are observed following a double‐blind, placebo‐controlled food challenge (DBPCFC) varies in clinical practice. There are little data on late reactions (LRs) following DBPCFCs. Therefore, we determined the prevalence, severity and clinical characteristics of late reactions in food‐allergic children and adolescents after DBPCFC, and ascertained which factors are associated...
BackgroundGenetic modification of allergenic foods such as apple has the potential to reduce their clinical allergenicity, but this has never been studied by oral challenges in allergic individuals.
MethodsWe performed oral food challenges in 21 apple‐allergic individuals with Elstar apples which had undergone gene silencing of the major allergen of apple, Mal d 1, by RNA interference. Downregulation...
BackgroundAlthough food allergy has universally been found to impair HRQL, studies have found significant differences in HRQL between countries, even when corrected for differences in perceived disease severity. However, little is known about factors other than disease severity which may contribute to HRQL in food‐allergic patients. Therefore, the aim of this study was to identify factors which may...
The aim of this study was to assess the genetic association of Filaggrin loss‐of‐function (FLGLOF) genetic variants with food allergy, and to investigate the added value of this test in diagnosing food allergy. Clinical reactivity to foods was diagnosed by the gold standard, the double‐blind, placebo‐controlled food challenge. Of 155 children, 33 (21.3%) children had at least one FLGLOF variant, and...
This is one of seven interlinked systematic reviews undertaken on behalf of the European Academy of Allergy and Clinical Immunology as part of their Guidelines for Food Allergy and Anaphylaxis, which focuses on instruments developed for IgE‐mediated food allergy. Disease‐specific questionnaires are significantly more sensitive than generic ones in measuring the response to interventions or future...
Instruments have been developed and validated for the measurement of health‐related quality of life in patients with food allergy. This guideline has been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines for Food Allergy and Anaphylaxis Group. It draws on a systematic review of the literature on quality of life instruments for food allergy and the Appraisal...
To cite this article: van der Velde JL, Flokstra‐de Blok BMJ, Hamp A, Knibb RC, Duiverman EJ, Dubois AEJ. Adolescent–parent disagreement on health‐related quality of life of food‐allergic adolescents: who makes the difference? Allergy 2011; 66: 1580–1581.
AbstractBackground: Food‐allergic adolescents are at highest risk for food allergy fatalities, which may be partly due to compromised self‐management...
To cite this article: Flokstra‐de Blok BMJ, van der Velde JL, Vlieg‐Boerstra BJ, Oude Elberink JNG, DunnGalvin A, Hourihane JO’B, Duiverman EJ, Dubois AEJ. Health‐related quality of life of food allergic patients measured with generic and disease‐specific questionnaires. Allergy 2010; 65: 1031–1038.
AbstractBackground: Health‐related quality of life (HRQL) has never been measured with both generic...
To cite this article: van der Velde JL, Flokstra‐de Blok BMJ, Vlieg‐Boerstra BJ, Oude Elberink JNG, DunnGalvin A, Hourihane JO’B, Duiverman EJ, Dubois AEJ. Development, validity and reliability of the food allergy independent measure (FAIM). Allergy 2010; 65: 630–635.
AbstractBackground: The Food Allergy Quality of Life Questionnaire‐Child Form, ‐Teenager Form and ‐Adult Form (FAQLQ‐CF, ‐TF and...
To cite this article: Flokstra‐de Blok BMJ, Dubois AEJ, Vlieg‐Boerstra BJ, Oude Elberink JNG, Raat H, DunnGalvin A, Hourihane JO’B, Duiverman EJ. Health‐related quality of life of food allergic patients: comparison with the general population and other diseases. Allergy 2010; 65: 238–244.
AbstractBackground: To date no studies have compared generic health‐related quality of life (HRQL) of food allergic...
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