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Objective: Elevated tumour necrosis factor-alpha (TNF-α) production in adipose tissue has been associated with obesity. We investigated whether mononuclear cell production of TNF-α decreased with weight loss in an obese population. Research methods and procedures: Seventeen obese patients with type 2 diabetes (BMI 32.5+/-0.9kg/m 2 ) and 33 obese, non-diabetic controls (BMI 31.2+/-0.5kg/m ...
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