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A synthetic approach to 4a‐carba‐d‐lyxofuranose derivatives starting from d‐lyxose is described. The protected 4a‐carba‐β‐d‐lyxofuranose was employed as the key intermediate for the synthesis of 4a‐carba‐d‐lyxofuranose derivatives including novel 1‐amino‐1‐deoxy‐4a‐carba‐d‐lyxofuranoses. Synthesized 4a‐carba‐d‐lyxofuranoses were evaluated as inhibitors of GH38 α‐mannosidases, namely, the Golgi (GMIIb)...
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