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Study Objective: A prospective, randomized controlled trial of new-onset atrial fibrillation was conducted to compare the efficacy and safety of sotalol and amiodarone (active treatment) with rate control by digoxin alone for successful reversion to sinus rhythm at 48 hours. Methods: We prospectively randomly assigned 120 patients with atrial fibrillation of less than 24 hours' duration to treatment...
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