Search results for: Masashi Ishida

Items from 1 to 20 out of 22 results

article

Heme oxygenase-1 prevents glucocorticoid and hypoxia-induced apoptosis and necrosis of osteocyte-like cells

Hiroki Yamamoto, Masazumi Saito, Tsuyoshi Goto, Keiichiro Ueshima, more

Medical Molecular Morphology > 2019 > 52 > 3 > 173-180

Glucocorticoids and hypoxia is considered to promote osteocyte apoptosis and necrosis, which are observed in glucocorticoid-associated osteonecrosis and osteoporosis. Heme oxygenase-1 (HO-1) induced by hemin is reported to have cytoprotective effects in ischemic diseases. The objective of this study was to evaluate the effect of HO-1 on osteocyte death caused by glucocorticoids and hypoxia. We confirmed...

article

Mass production of fertilized eggs by artificial insemination from captive-reared Pacific bluefin tuna (Thunnus orientalis)

Taku Endo, Masashi Ishida, Ryosuke Yazawa, Yutaka Takeuchi, more

Aquaculture > 2016 > 451 > C > 72-77

Artificial insemination (AI) techniques for obtaining fertilized eggs from captive-reared ~3- to 4-year-old Pacific bluefin tuna (Thunnus orientalis) were developed. Gametes for AI were acquired from fish harvested from commercial offshore sea cages. Sperm was successfully obtained from almost all male fish, whereas the occurrence of ovulated eggs was relatively low. Therefore, the AI was dependent...

article

Femoral perfusion after pulsed electromagnetic field stimulation in a steroid‐induced osteonecrosis model

Akira Ikegami, Keiichiro Ueshima, Masazumi Saito, Kazuya Ikoma, more

Bioelectromagnetics > 36 > 5 > 349 - 357

This study was designed to evaluate femoral perfusion after pulsed electromagnetic field (PEMF) stimulation in a steroid‐induced osteonecrosis rabbit model by dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI). Steroid‐induced osteonecrosis was produced by single intramuscular injection of methylprednisolone in 15 rabbits. Eight rabbits underwent PEMF stimulation (PEMF group) and seven...

article

Evaluation of femoral perfusion in a rabbit model of steroid‐induced osteonecrosis by dynamic contrast‐enhanced mri with a high magnetic field MRI system

Shigeki Hayashi, Mikihiro Fujioka, Kazuya Ikoma, Masazumi Saito, more

Journal of Magnetic Resonance Imaging > 41 > 4 > 935 - 940

Purpose To evaluate perfusion during the early phase after steroid administration in vivo using dynamic contrast‐enhanced magnetic resonance imaging (DCE‐MRI) with a high magnetic field MRI system. The main pathogenesis of steroid‐induced osteonecrosis is considered to be ischemia. Materials and Methods A single dose of methylprednisolone (MPSL) was injected into nine rabbits. DCE‐MRI was performed...

article

Dissolving 4-manifolds, covering spaces and Yamabe invariant

Anar Akhmedov, Masashi Ishida, B. Doug Park

Annals of Global Analysis and Geometry > 2015 > 47 > 3 > 271-283

We construct new spin and nonspin 4-manifolds with zero signature that dissolve after a connected sum with only one copy of $$S^{2} \times S^{2}$$ S 2 × S 2 . We use these 4-manifolds to construct new examples of 4-manifolds with negative Yamabe invariant and whose universal covers have positive Yamabe invariant. In particular, these provide new spin and nonspin counterexamples to a...

article

Harnack estimates for nonlinear heat equations with potentials in geometric flows

Hongxin Guo, Masashi Ishida

manuscripta mathematica > 2015 > 148 > 3-4 > 471-484

Let M be a closed Riemannian manifold with a family of Riemannian metrics $${g_{\it ij}(t)}$$ g ij ( t ) evolving by geometric flow $${\partial_{t}g_{\it ij} = -2{S}_{\it ij}}$$ ∂ t g ij = - 2 S ij , where $${S_{\it ij}(t)}$$ S ij ( t ) is a family of smooth symmetric two-tensors on M. In this paper we derive differential Harnack estimates for positive...

article

Harnack estimates for nonlinear backward heat equations in geometric flows

Hongxin Guo, Masashi Ishida

Journal of Functional Analysis > 2014 > 267 > 8 > 2638-2662

Let M be a closed Riemannian manifold with a family of Riemannian metrics gij(t) evolving by a geometric flow ∂tgij=−2Sij, where Sij(t) is a family of smooth symmetric two-tensors. We derive several differential Harnack estimates for positive solutions to the nonlinear backward heat-type equation∂f∂t=−Δf+γflog⁡f+aSf where a and γ are constants and S=gijSij is the trace of Sij. Our abstract formulation...

article

Geometric flows and differential Harnack estimates for heat equations with potentials

Masashi Ishida

Annals of Global Analysis and Geometry > 2014 > 45 > 4 > 287-302

Let $$M$$ M be a closed Riemannian manifold with a Riemannian metric $$g_{ij}(t)$$ g i j ( t ) evolving by a geometric flow $$\partial _{t}g_{ij} = -2{S}_{ij}$$ ∂ t g i j = - 2 S i j , where $$S_{ij}(t)$$ S i j ( t ) is a symmetric two-tensor on $$(M, g(t))$$ ( M , g ( t ) ) . Suppose that $$S_{ij}$$ S i j satisfies...

article

Families of 4-Manifolds with Nontrivial Stable Cohomotopy Seiberg–Witten Invariants, and Normalized Ricci Flow

R. İnanç Baykur, Masashi Ishida

The Journal of Geometric Analysis > 2014 > 24 > 4 > 1716-1736

In this article, we produce infinite families of 4-manifolds with positive first Betti numbers and meeting certain conditions on their homotopy and smooth types so as to conclude the non-vanishing of the stable cohomotopy Seiberg–Witten invariants of their connected sums. Elementary building blocks used in Ishida and Sasahira ( arXiv:0804.3452 , 2008) are shown to be included in our general construction...

article

The Pacific bluefin tuna (Thunnus orientalis) dead end gene is suitable as a specific molecular marker of type A spermatogonia

Ryosuke Yazawa, Yutaka Takeuchi, Tetsuro Morita, Masashi Ishida, more

Molecular Reproduction and Development > 80 > 10 > 871 - 880

We developed a spermatogonial transplantation technique to produce donor‐derived gametes in surrogate fish. Our ultimate aim is to establish surrogate broodstock that can produce bluefin tuna. We previously determined that only type A spermatogonia (ASG) could colonize recipient gonads in salmonids. Therefore, it is necessary to develop a precise molecular marker that can distinguish ASG in order...

article

Noninvasive up-regulation of angiopoietin-2 and fibroblast growth factor-2 in bone marrow by pulsed electromagnetic field therapy

Tsuyoshi Goto, Mikihiro Fujioka, Masashi Ishida, Masaaki Kuribayashi, more

Journal of Orthopaedic Science > 2010 > 15 > 5 > 661-665

Background Pulsed electromagnetic field (PEMF) therapy has been widely used in clinical practice for bone fracture healing. However, the mechanism of its action remains to be elucidated. Our object was to investigate the mechanism by which PEMF accelerates bone fracture healing. Methods We used 20 mice in this study. Ten mice received PEMF for 10 h/day for 1 week via the coils of a PEMF stimulation...

article

Smooth structures, normalized Ricci flows, and finite cyclic groups

Masashi Ishida, Ioana Şuvaina

Annals of Global Analysis and Geometry > 2009 > 35 > 3 > 267-275

A solution to the normalized Ricci flow is called non-singular if it exists for all time with uniformly bounded sectional curvature. By using the techniques developed by the present authors [Ishida, The normalized Ricci flow on four-manifolds and exotic smooth structures; Şuvaina, Einstein metrics and smooth structures on non-simply connected 4-manifolds] we prove that for any finite cyclic group...

article

On normalized Ricci flow and smooth structures on four-manifolds with b ⁺ = 1

Masashi Ishida, Rareş Răsdeaconu, Ioana Şuvaina

Archiv der Mathematik > 2009 > 92 > 4 > 355-365

. We find an obstruction to the existence of non-singular solutions to the normalized Ricci flow on four-manifolds with b ⁺ = 1. By using this obstruction, we study the relationship between the existence or non-existence of non-singular solutions of the normalized Ricci flow and exotic smooth structures on the topological 4-manifolds $$\mathbb{C}P^{2} {\# \ell}{\overline{{\mathbb{C}}P^2}}$$...

article

Electromagnetic Fields

Masashi Ishida, Mikihiro Fujioka, Kenji A. Takahashi, Yuji Arai, more

Clinical Orthopaedics and Related Research® > 2008 > 466 > 5 > 1068-1073

Establishing a means to prevent osteonecrosis after corticosteroid administration is an important theme. We asked whether pulsed electromagnetic field stimulation, a noninvasive treatment, could prevent osteonecrosis. Ninety rabbits were divided into four treatment groups: (1) exposure of 10 hours per day to electromagnetic stimulation for 1 week, followed by injection of methylprednisolone (20 mg/kg),...

article

ApoB C7623T polymorphism predicts risk for steroid-induced osteonecrosis of the femoral head after renal transplantation

Tetsurou Hirata, Mikihiro Fujioka, Kenji A. Takahashi, Yuji Arai, more

Journal of Orthopaedic Science > 2007 > 12 > 3 > 199-206

Background Nontraumatic osteonecrosis of the femoral head (ONFH) is caused by disruption of blood flow. This disease often occurs in association with steroid treatment. The pathology of steroid-induced ONFH remains unclear, although abnormalities in lipid metabolism have been reported to be involved. In this study, we examined the differences of gene polymorphism frequencies of apolipoprotein B (ApoB)...

article

InP buried growth of SiO2 wires toward reduction of collector capacitance in HBT

Yasuyuki Miyamoto, Masashi Ishida, Tohru Yamamoto, Tsukasa Miura, more

Journal of Crystal Growth > 2007 > 298 > Complete > 867-870

A new heterojunction bipolar transistor (HBT) structure with buried SiO ₂ wires is proposed. SiO ₂ wires were buried in the InP layer by metalorganic vapor-phase epitaxy (MOVPE). The insertion of SiO ₂ wires under the base electrodes reduces collector capacitance because of a small dielectric constant. Two SiO ₂ wires of 200nm width and 60nm height on the InP substrate...

article

Perelman’s invariant, Ricci flow, and the Yamabe invariants of smooth manifolds

Kazuo Akutagawa, Masashi Ishida, Claude LeBrun

Archiv der Mathematik > 2007 > 88 > 1 > 71-76

. In his study of Ricci flow, Perelman introduced a smooth-manifold invariant called $$\bar{\lambda}$$ . We show here that, for completely elementary reasons, this invariant simply equals the Yamabe invariant, alias the sigma constant, whenever the latter is non-positive. On the other hand, the Perelman invariant just equals +∞ whenever the Yamabe invariant is positive.

article

Single-wall carbon nanotubes encaging linear chain C10H2 polyyne molecules inside

Daisuke Nishide, Hirofumi Dohi, Tomonari Wakabayashi, Eiji Nishibori, more

Chemical Physics Letters > 2006 > 428 > 4-6 > 356-360

A new hybrid material C ₁₀ H ₂ @SWNTs, single-wall carbon nanotubes (SWNTs) encapsulating C ₁₀ H ₂ polyyne molecules, has been synthesized and confirmed by Raman spectroscopy and X-ray diffraction measurement. The C ₁₀ H ₂ polyyne molecules composed of linearly bonded sp-carbon atoms are aligned inside the SWNTs. This hybrid material exhibits a characteristic...

article

Defect-Induced Atomic Migration in Carbon Nanopeapod: Tracking the Single-Atom Dynamic Behavior

Koki Urita, Yuta Sato, Kazu Suenaga, Alexandre Gloter, more

Nano Letters > 2004 > 4 > 12 > 2451 - 2454

article

A randomized open-label comparative study of conventional therapy versus mizoribine onlay therapy in patients with steroid-resistant nephrotic syndrome (postmarketing survey)

Toshiaki Shibasaki, Akio Koyama, Akira Hishida, Eri Muso, more

Clinical and Experimental Nephrology > 2004 > 8 > 2 > 117-126

Background. A previous double-blind 24-week clinical trial of mizoribine (MZ) vs placebo in steroid-resistant primary nephrotic syndrome (SRPNS) showed that MZ was more effective than placebo in reducing the rate of deterioration of renal function. The present study was conducted to evaluate the efficacy and safety of MZ in patients with SRPNS after 2 years treatment. Methods. A multicenter randomized...

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INFONA - science communication portal

Search results for: Masashi Ishida

Heme oxygenase-1 prevents glucocorticoid and hypoxia-induced apoptosis and necrosis of osteocyte-like cells

Mass production of fertilized eggs by artificial insemination from captive-reared Pacific bluefin tuna (Thunnus orientalis)

Femoral perfusion after pulsed electromagnetic field stimulation in a steroid‐induced osteonecrosis model

Evaluation of femoral perfusion in a rabbit model of steroid‐induced osteonecrosis by dynamic contrast‐enhanced mri with a high magnetic field MRI system

Dissolving 4-manifolds, covering spaces and Yamabe invariant

Harnack estimates for nonlinear heat equations with potentials in geometric flows

Harnack estimates for nonlinear backward heat equations in geometric flows

Geometric flows and differential Harnack estimates for heat equations with potentials

Families of 4-Manifolds with Nontrivial Stable Cohomotopy Seiberg–Witten Invariants, and Normalized Ricci Flow

The Pacific bluefin tuna (Thunnus orientalis) dead end gene is suitable as a specific molecular marker of type A spermatogonia

Noninvasive up-regulation of angiopoietin-2 and fibroblast growth factor-2 in bone marrow by pulsed electromagnetic field therapy

Smooth structures, normalized Ricci flows, and finite cyclic groups

On normalized Ricci flow and smooth structures on four-manifolds with b ⁺ = 1

Electromagnetic Fields

ApoB C7623T polymorphism predicts risk for steroid-induced osteonecrosis of the femoral head after renal transplantation

InP buried growth of SiO2 wires toward reduction of collector capacitance in HBT

Perelman’s invariant, Ricci flow, and the Yamabe invariants of smooth manifolds

Single-wall carbon nanotubes encaging linear chain C10H2 polyyne molecules inside

Defect-Induced Atomic Migration in Carbon Nanopeapod: Tracking the Single-Atom Dynamic Behavior

A randomized open-label comparative study of conventional therapy versus mizoribine onlay therapy in patients with steroid-resistant nephrotic syndrome (postmarketing survey)

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