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Specific Alterations in Brain White Matter Networks and Their Impact on Clinical Function in Pediatric Patients With Thoracolumbar Spinal Cord Injury

Beining Yang, Weimin Zheng, Ling Wang, Yulong Jia, więcej

Journal of Magnetic Resonance Imaging > 60 > 5 > 1842 - 1852

Background The alternation of brain white matter (WM) network has been studied in adult spinal cord injury (SCI) patients. However, the WM network alterations in pediatric SCI patients remain unclear. Purpose To evaluate WM network changes and their functional impact in children with thoracolumbar SCI (TSCI). Study Type Prospective. Subjects Thirty‐five pediatric patients with TSCI (8.94 ±...

artykuł

Customizing Aniline‐Derived Molecular Structures to Attain beyond 22 % Efficient Inorganic Perovskite Solar Cells

Rui Li, Shiang Zhang, Hao Zhang, Zhiteng Wang, więcej

Angewandte Chemie > 136 > 42 > n/a - n/a

The characteristics of the soft component and the ionic‐electronic nature in all‐inorganic CsPbI_3‐xBr_x perovskite typically lead to a significant number of halide vacancy defects and ions migration, resulting in a reduction in both photovoltaic efficiency and stability. Herein, we present a tailored approach in which both anion‐fixation and undercoordinated‐Pb passivation are achieved in situ during...

artykuł

Customizing Aniline‐Derived Molecular Structures to Attain beyond 22 % Efficient Inorganic Perovskite Solar Cells

Rui Li, Shiang Zhang, Hao Zhang, Zhiteng Wang, więcej

Angewandte Chemie International Edition > 63 > 42 > n/a - n/a

artykuł

Vacuolar recruitment of retromer by a SNARE complex enables infection‐related trafficking in rice blast

Xin Chen, Jiexiong Hu, Haoming Zhong, Qiuqiu Wu, więcej

New Phytologist > 244 > 3 > 997 - 1012

The retromer complex is a conserved sorting machinery that maintains cellular protein homeostasis by transporting vesicles containing cargo proteins to defined destinations. It is known to sort proteins at the vacuole membranes for retrograde trafficking, preventing their degradation in the vacuole. However, the detailed mechanism of retromer recruitment to the vacuole membrane has not yet been...

artykuł

Peripheral blood MR1 tetramer‐positive mucosal‐associated invariant T‐cell function is modulated by mammalian target of rapamycin complex 1 in patients with active tuberculosis

Chao‐Ying Zhou, Ya‐Long Yang, Zhen‐Yu Han, Yao‐Xin Chen, więcej

Immunology > 173 > 3 > 497 - 510

Tuberculosis (TB) is still an urgent global public health problem. Notably, mucosal‐associated invariant T (MAIT) cells play an important role in early anti‐TB immune response. Targeted control of them may be an effective method to improve vaccine efficacy and TB treatment. However, the biology and signal regulation mechanisms of MAIT cells in TB patients are still poorly understood. Previous studies...

artykuł

Bifunctional Oxygen‐Defect Bismuth Catalyst toward Concerted Production of H₂O₂ with over 150% Cell Faradaic Efficiency in Continuously Flowing Paired‐Electrosynthesis System

Qiqi Zhang, Changsheng Cao, Shenghua Zhou, Wenbo Wei, więcej

Advanced Materials > 36 > 39 > n/a - n/a

The electrosynthesis of hydrogen peroxide (H₂O₂) from O₂ or H₂O via the two‐electron (2e⁻) oxygen reduction (2e⁻ ORR) or water oxidation (2e⁻ WOR) reaction provides a green and sustainable alternative to the traditional anthraquinone process. Herein, a paired‐electrosynthesis tactic is reported for concerted H₂O₂ production at a high rate by coupling the 2e⁻ ORR and 2e⁻ WOR, in which the bifunctional...

artykuł

Anchoring Cs⁺ Ions on Carbon Vacancies for Selective CO₂ Electroreduction to CO at High Current Densities in Membrane Electrode Assembly Electrolyzers

Yanhui Sun, Junxiang Chen, XueMei Du, Jiwei Cui, więcej

Angewandte Chemie International Edition > 63 > 40 > n/a - n/a

Electrolyte cations have been demonstrated to effectively enhance the rate and selectivity of the electrochemical CO₂ reduction reaction (CO₂RR), yet their implementation in electrolyte‐free membrane electrode assembly (MEA) electrolyzer presents significant challenges. Herein, an anchored cation strategy that immobilizes Cs⁺ on carbon vacancies was designed and innovatively implemented in MEA electrolyzer,...

artykuł

Anchoring Cs⁺ Ions on Carbon Vacancies for Selective CO₂ Electroreduction to CO at High Current Densities in Membrane Electrode Assembly Electrolyzers

Yanhui Sun, Junxiang Chen, XueMei Du, Jiwei Cui, więcej

Angewandte Chemie > 136 > 40 > n/a - n/a

artykuł

Interference of ATP‐Adenosine Axis by Engineered Biohybrid for Amplifying Immunogenic Cell Death‐Mediated Antitumor Immunotherapy

Xin‐Chen Deng, Jun‐Long Liang, Shi‐Man Zhang, Yu‐Zhang Wang, więcej

Advanced Materials > 36 > 36 > n/a - n/a

Immunogenic cell death (ICD) often results in the production and accumulation of adenosine (ADO), a byproduct that negatively impacts the therapeutic effect as well as facilitates tumor development and metastasis. Here, an innovative strategy is elaborately developed to effectively activate ICD while avoiding the generation of immunosuppressive adenosine. Specifically, ZIF‐90, an ATP‐responsive consumer,...

artykuł

Improvement of Perovskite Solar Cells Efficiency by Management of the Electron Withdrawing Groups in Hole Transport Materials: Theoretical Calculation and Experimental Verification

Jiayi Qi, Ruiqin Wang, Ye Zeng, Xing Gao, więcej

Small > 20 > 36 > n/a - n/a

Management of functional groups in hole transporting materials (HTMs) is a feasible strategy to improve perovskite solar cells (PSCs) efficiency. Therefore, starting from the carbazole–diphenylamine‐based JY7 molecule, JY8 and JY9 molecules are incorporated into the different electron‐withdrawing groups of fluorine and cyano groups on the side chains. The theoretical results reveal that the introduction...

artykuł

Electrocatalytic Conversion of Nitrate Into Ammonia Through Heterogeneous Catalysis of NiMoO₄ and Cu/Cu₂O

Changzheng Lin, Xin Chen, Ling Wang, Weijia Li, więcej

Advanced Functional Materials > 34 > 36 > n/a - n/a

Facilitating equilibrium in the nitrogen cycle, electrochemical nitrate reduction (NitRR) to ammonia stands as a carbon‐free method for ammonia synthesis. Copper‐based catalysts, renowned for NitRR, face a hurdle in supplying sufficient hydrogen radicals (*H) for efficient hydrogenation of NitRR intermediates. Addressing this, NiMoO₄ is leveraged as an excellent *H donor, synergistically coupling...

artykuł

Selective laser sintering and spark plasma sintering of (Zr,Nb,Ta,Ti,W)C compositionally complex carbide ceramics

Lanh Trinh, Zilong Hua, Kaustubh Bawane, Lingfeng He, więcej

Journal of the American Ceramic Society > 107 > 11 > 7175 - 7188

Two advanced manufacturing processes, spark plasma sintering (SPS) and selective laser sintering (SLS), have been developed for synthesis of (Zr,Nb,Ta,Ti,W)C compositionally complex carbide (CCC) via reactive sintering of a powder mixture of constitute monocarbides. X‐ray diffraction analysis confirmed that the single‐phase CCC can be formed by both SPS and SLS. While a homogenous microstructure with...

artykuł

Unpaired fundus image enhancement based on constrained generative adversarial networks

Luyao Yang, Shenglan Yao, Pengyu Chen, Mei Shen, więcej

Journal of Biophotonics > 17 > 9 > n/a - n/a

Fundus photography (FP) is a crucial technique for diagnosing the progression of ocular and systemic diseases in clinical studies, with wide applications in early clinical screening and diagnosis. However, due to the nonuniform illumination and imbalanced intensity caused by various reasons, the quality of fundus images is often severely weakened, brings challenges for automated screening, analysis,...

artykuł

Synergistic Regulation of Targeted Organelles in Tumor Cells to Promote Photothermal‐Immunotherapy Using Intelligent Core‐Satellite‐Like Nanoparticles for Effective Treatment of Breast Cancer

Xiaowei Chang, Xiaoyu Tang, Wenjun Tang, Lin Weng, więcej

Small > 20 > 35 > n/a - n/a

The normal operation of organelles is critical for tumor growth and metastasis. Herein, an intelligent nanoplatform (BMA_EF) is fabricated to perform on‐demand destruction of mitochondria and golgi apparatus, which also generates the enhanced photothermal‐immunotherapy, resulting in the effective inhibition of primary and metastasis tumor. The BMA_EF has a core of mesoporous silica nanoparticles loaded...

artykuł

Emergent constraints on historical and future global gross primary productivity

Xin Chen, Tiexi Chen, Yi Y. Liu, Bin He, więcej

Global Change Biology > 30 > 8 > n/a - n/a

Terrestrial gross primary productivity (GPP) is the largest carbon flux in the global carbon cycle and plays a crucial role in terrestrial carbon sequestration. However, historical and future global GPP estimates still vary markedly. In this study, we reduced uncertainties in global GPP estimates by employing an innovative emergent constraint method on remote sensing‐based GPP datasets (RS‐GPP), using...

artykuł

Distinct brain network patterns in complete and incomplete spinal cord injury patients based on graph theory analysis

Beining Yang, Haotian Xin, Ling Wang, Qunya Qi, więcej

CNS Neuroscience & Therapeutics > 30 > 8 > n/a - n/a

Aims To compare the changes in brain network topological properties and structure–function coupling in patients with complete spinal cord injury (CSCI) and incomplete spinal cord injury (ICSCI), to unveil the potential neurobiological mechanisms underlying the different effects of CSCI and ICSCI on brain networks and identify objective neurobiological markers to differentiate between CSCI and ICSCI...

artykuł

Structural Design of Multifunctional PET Non‐woven Fabric with Porous Dual‐Network for Infrared Stealth, Flame Retardant, and Electromagnetic Interference Shielding

Yang Bai, Jianyan Feng, Peng Wang, Xin Chen, więcej

Advanced Engineering Materials > 26 > 16 > n/a - n/a

With rapid advances in electronic and communication technology, electromagnetic interference and other problems are becoming increasingly prominent. Thus, electromagnetic interference shielding materials have recently garnered extensive attention. In this study, a multi‐walled carbon nanotube/polyurethane/non‐woven electromagnetic shielding material (CPNW) is developed using impregnation and nonsolvent‐induced‐phase...

artykuł

Distributed fast F‐T control for UAV formation in the presence of unknown input disturbances

Hongjin Liao, Xin Chen, Jiangbo Jia, Guangyuan Zhu

International Journal of Robust and Nonlinear Control > 34 > 14 > 9984 - 10008

This paper addresses the problem of fixed‐time (F‐T) control for unmanned aerial vehicle (UAV) formation under unknown input disturbances to achieve moving target tracking. First, a kinematic model with uncertainties is employed to analyze the transient response of the UAV formation accurately. Next, based on a fast F‐T lemma, an F‐T disturbance observer is constructed to estimate the unknown disturbances...

artykuł

Insight into the relationship between interfacial structure and thermal conductivity in epoxy resin/Al₂O₃ composite

Jian Qiao, Yang Lv, Yun Chen, Wei Yang, więcej

Polymer Composites > 45 > 12 > 11112 - 11124

The relationship between interfacial structure and thermal conductivity in epoxy resin/Al₂O₃ composite is important but is still elusive. Here, we illuminate this issue by investigating the role of four silane coupling agents in thermal conductivity for epoxy resin/Al₂O₃ composites. The results show that 3‐glycidoxypropyltrimethoxysilane (KH560) is the best silane coupling agent to modify Al₂O₃,...

artykuł

Who matters and why? The contributions of different sources of social support to doctoral students' academic engagement

Fei Cao, Huan Li, Xin Chen, Yanwei You, więcej

European Journal of Education > 59 > 3 > n/a - n/a

Social support is a crucial factor in the academic engagement of doctoral students, which is vital to their overall success. While past studies have mostly focused on the support from doctoral supervisors, support from other significant groups, including institutions, peers and families, has been largely neglected, and even no study has investigated their contributions to doctoral students' development...

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