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Tissue Engineering
In article 2205614, Anthony S. Weiss and co‐workers report a nonporous vascular graft from tropoelastin and polyglycerol sebacate that converts into a neoartery, with cellular and extracellular matrix structures approximating the native aorta. The resulting neoartery comprises an internal elastic lamina and multiple elastic lamellae sandwiched between circumferentially aligned smooth...
Native arteries contain a distinctive intima‐media composed of organized elastin and an adventitia containing mature collagen fibrils. In contrast, implanted biodegradable small‐diameter vascular grafts do not present spatially regenerated, organized elastin. The elastin‐containing structures within the intima‐media region encompass the elastic lamellae (EL) and internal elastic lamina (IEL) and are...
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