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In the mammalian retina, somatostatin (SRIF-14) acts through distinct receptor subtypes (sst15). Among them, sst2 has been localized to numerous retinal cells, including photoreceptors and rod bipolar cells (RBCs). The specific role of sst2 in the retina is largely undetermined. In this study, we characterized retinas of mice with targeted deletion of sst2 (sst2 KO) and we investigated functions of...
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