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In the n‐alkane‐assimilating yeast Yarrowia lipolytica, the transcription of ALK1, encoding cytochrome P450, that catalyses n‐alkane hydroxylation is activated by a complex composed of Yas1p and Yas2p via a promoter element, ARE1, in response to n‐alkanes. An Opi1‐family transcription factor, Yas3p, represses the transcription by binding to Yas2p in the nucleus when cultured in glucose‐containing...
The yeast Yarrowia lipolytica assimilates n‐alkanes or fatty acids as carbon sources. Transcriptional activation by n‐alkanes of ALK1 encoding a cytochrome P450 responsible for the terminal hydroxylation has been well studied so far, but its regulation by other carbon sources is poorly understood. Here, we analyzed the transcriptional regulation of ALK1 by glycerol. Glycerol is a preferable carbon...
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