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Annulus fibrosus is critical to bear loads and resist fluid flow in the intervertebral disc. However, the detailed biomechanical mechanism of annulus fibrosus under abnormal loading is still ambiguous, especially at the micro and nano scales. This study aims to characterize the alterations of modulus at the nano scale of individual collagen fibrils in annulus fibrosus after in‐situ immobilization,...
Objective
To evaluate how well different magnitudes of compression‐induced degenerative changes using a bent rat tail model simulated human lumbar lordosis. It has been shown that compression plays an important role in intervertebral disc degeneration (IDD).
Methods
Sprague–Dawley rats (n = 25) were instrumented with a special compressive apparatus that was used to bend the intervertebral disc...
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