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Multimodal microendoscopes enable co‐located structural and molecular measurements in vivo, thus providing useful insights into the pathological changes associated with disease. However, different optical imaging modalities often have conflicting optical requirements for optimal lens design. For example, a high numerical aperture (NA) lens is needed to realize high‐sensitivity fluorescence measurements...
Multimodal Microendoscopy
In article number 2107032, Jiawen Li and co‐workers use two‐photon 3D printing to develop a 330 micron diameter lens optimized for both fluorescence imaging and optical coherence tomography. This lens‐in‐lens design is incorporated in an intravascular imaging catheter offering improved performance for heart disease detection.
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