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Haemophilus parasuis is a respiratory commensal in healthy piglets, but can also produce invasive disease and meningitis, which requires the ability to cross the blood–brain barrier. This study determined the capacity of well-characterised virulent and non-virulent strains of H. parasuis, as well as other field strains, to adhere to and invade PBMEC/C1-2 endothelial cells. Virulent strains were derived...
Streptococcus suis is a major pathogen of swine, causing mainly meningitis, and it also represents an emerging zoonotic agent. We investigated its ability to induce the release of pro-inflammatory cytokines and chemokines by porcine brain microvascular endothelial cells (PBMEC). We demonstrated that live S. suis induced a strong release of interleukin (IL)-6 and IL-8 by PBMEC. We showed that the suilysin...
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