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Rat pancreatic zymogen granules were analyzed using flow cytometry to determine their heterogeneity with respect to different characteristics such as size (FSC), internal complexity (SSC) and membrane permeability to lipophilic and cationic dyes using rhodamine-123 as probe. Differences in the chemical composition of the membrane were determined using FITC-labeled lectins (concanavalin A, Wheat germ...
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