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Aim
Recently, serum hepatitis B virus (HBV)‐RNA has been reported to be detectable even when HBV particle production is inhibited by nucleot(s)ide analogues (NAs). However, the dynamics of the HBV‐RNA sequence compared with those of HBV‐DNA during the emergence of antiviral resistance are yet to be elucidated.
Methods
First, we quantified serum HBV‐RNA in 181 infected patients, and its relationships...
Aim
Although the viral markers hepatitis B surface antigen (HBsAg) and hepatitis B core‐related antigen (HbcrAg) could reflect intrahepatic hepatitis B virus (HBV) replication activity and constitute important biomarkers for hepatocellular carcinoma (HCC), the value of using these two markers in combination for assessing HCC risk has not been clarified in detail.
Methods
Four hundred and forty‐nine...
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