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In previous studies, we found that IFNγ and TNFα generated by activated macrophages stimulate the metastatic potential in F10-M3 cells, a clone isolated from B16-F10 murine melanoma line. In this phenomenon, TNFα promoted the expression of a metastatic phenotype in tumor cells previously primed with IFNγ. Here, we demonstrate that IFNα or IFNβ may replace IFNγ in priming tumor cells. We also noticed...
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