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Narcolepsy–cataplexy is characterised by orexin deficiency, sleep disturbance, obesity and dysautonomia. Ghrelin and obestatin affect both energy intake and sleep. Our aim was to investigate ghrelin, obestatin and metabolic/autonomic function in narcolepsy–cataplexy. Eight narcolepsy–cataplexy patients (seven CSF orexin-deficient) and eight matched controls were studied. The subjects had a fixed energy...
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