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The influence of the solvent content on the solution‐mediated phase transformation of sulfadiazine (SD) N‐methyl pyrrolidone (NMP) solvate into SD was investigated for process development. The solubility results of the NMP solvate and SD in NMP solvent/water mixtures supported by the analysis of solvent‐solvent interactions between NMP solvent molecules were used to understand and optimize the transformation...
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