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Raman spectroscopy has been shown to have the potential for revealing oxygenated and spin ability of hemoglobin. In this study, confocal micro‐Raman spectroscopy is developed to monitor the effect of sodium nitrite on oxyhemoglobin (HbO2) in whole blood. We observe that the band at 1,638 cm−1 which is sensitive to the oxidation state decreases dramatically, while the 1,586 cm−1 (low‐spin state band)...
Second harmonic microscopic imaging and spectroscopy technology has become a powerful tool for biomedical studies, especially in fibrosis‐related diseases research. And type I collagen is the major risk factors for fibrotic diseases. In this study, model for three‐dimensional (3‐D) uniform arrangement type I collagen is set up for researching the second harmonic generation (SHG) on nonlinear optics...
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