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AimTo examine the effects of combination with levamlodipine and bisoprolol on stroke in rats.
MethodsFor acute study, Systolic blood pressure (SBP) and heart period (HP) were monitored in conscious stroke prone‐spontaneously hypertensive rats (SHR‐SP) and sinoaortic denervation (SAD) rats before and after intragastric administration of either drug at a single dose. Rats were subjected to middle cerebral...
Aims: Stroke is a major cause of disability and death worldwide. Hypertension is one of the most important risk factors for stroke. The objective of this work was to study the synergic effects of levamlodipine and bisoprolol on blood pressure reduction and organ protection in spontaneously hypertensive rats (SHR). Methods: Blood pressure was continuously monitored in conscious SHR. For acute study,...
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