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Aims
Wisteria floribunda agglutinin (WFA)‐positive human Mac‐2‐binding protein (WFA+‐M2BP) is a new glycol marker related to liver fibrosis. The aim of the present study was to evaluate WFA+‐M2BP as a predictor of hepatocellular carcinoma (HCC) development in patients with chronic hepatitis C.
Methods
This case–control study included 14 patients with chronic hepatitis C who developed HCC and 52controls,...
BACKGROUNDA new predictive biomarker for determining prognosis in patients with hepatocellular carcinoma (HCC) who receive sorafenib is required, because achieving a reduction in tumor size with sorafenib is rare, even in patients who have a favorable prognosis. Vascular endothelial growth factor (VEGF) receptor is a sorafenib target. In the current study, the authors examined changes in plasma VEGF...
Background The FIB-4 index is a simple formula to predict liver fibrosis. This study aimed to evaluate the utility of the FIB-4 index and associated time-course changes as a predictor of hepatocellular carcinoma (HCC) development. Methods A total of 171 chronic hepatitis C patients who underwent paired liver biopsies and 875 patients who underwent a single liver biopsy (validation group) were investigated...
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