Search results for: Mitsuko Yuzawa

Items from 1 to 20 out of 76 results

article

Baseline data from a multicenter, 5-year, prospective cohort study of Japanese age-related macular degeneration: an AMD2000 report

Akitaka Tsujikawa, Yumiko Akagi-Kurashige, Mitsuko Yuzawa, Tatsuro Ishibashi, more

Japanese Journal of Ophthalmology > 2018 > 62 > 2 > 127-136

Purpose To report research participants’ baseline characteristics in the AMD2000 study, a prospective, multicenter, 5-year, observational cohort study of Japanese age-related macular degeneration (AMD). The characteristics were determined using multimodal imaging. Methods Patients with AMD were recruited at 18 clinical sites in Japan between April 2006 and March 2009. Each patient underwent a complete...

article

A 5-year multicenter prospective cohort study on the long-term visual prognosis and predictive factors for visual outcome in Japanese patients with age-related macular degeneration: the AMD2000 study

Yumiko Akagi-Kurashige, Akitaka Tsujikawa, Mitsuko Yuzawa, Tatsuro Ishibashi, more

Japanese Journal of Ophthalmology > 2018 > 62 > 2 > 137-143

Purpose In this study (AMD2000), we aimed to determine the visual prognosis of Japanese patients with age-related macular degeneration (AMD). Methods This was a multicenter prospective observational cohort study. In total, 460 patients with AMD were recruited from April 2006 to March 2009 from 18 clinical trial sites in Japan. They were followed up for 5 years, as they continued to receive medical...

article

Wet laboratory training using porcine eyes with eyelids

Hiroyuki Nakashizuka, Yu Wakatsuki, Yumiko Machida, Yuko Okubo, more

Canadian Journal of Ophthalmology / Journal Canadien d'Ophtalmologie > 2017 > 52 > 4 > 398-402

This study aimed to evaluate the usefulness of a new wet laboratory (wet lab) system using porcine eyes with eyelids.Teaching device trial.Porcine eyes with orbital tissues and eyelids.Twenty porcine eyes with orbital tissues and eyelids were enucleated from pigs butchered at age 6 months. These eyes were positioned in the eye sockets of a model head and stabilized with a pin. Eye draping, dressing...

article

Reduced anterior chamber contamination by frequent surface irrigation with diluted iodine solutions during cataract surgery

Hiroyuki Shimada, Shinji Arai, Hiroyuki Nakashizuka, Takayuki Hattori, more

Acta Ophthalmologica > 95 > 5 > e373 - e378

Purpose To verify that ocular surface irrigation with 0.025% povidone–iodine (PI) or 0.0025% polyvinyl alcohol–iodine (PAI) during cataract surgery minimizes bacterial contamination of the anterior chamber. Methods The study was a prospective, interventional case series. First, the bactericidal effect of PI or PAI against Staphylococcus aureus was evaluated in vitro. Next, in 400 eyes undergoing...

article

Postoperative roll cake-like macular fold after retinal detachment surgery

Ryusaburo Mori, Hiroyuki Nakashizuka, Yumiko Machida, Hiroyuki Shimada, more

International Ophthalmology > 2018 > 38 > 2 > 767-770

Purpose To report a case developing a severe retinal fold (RF), resembling a roll cake on optical coherence tomography (OCT), after retinal detachment (RD) surgery. Case report A 61-year-old man underwent vitrectomy for a limited macula-on-superior rhegmatogenous RD and gas tamponade at another hospital. Despite remaining prone for 4 days, RF was noted after gas disappearance and he was referred...

article

Choroidal thickness findings in two siblings with nanophthalmos by swept source-OCT: a case report

Hiroyuki Kaneko, Ari Shinojima, Mori Ryusaburo, Akiyuki Kawamura, more

BMC Research Notes > 2017 > 10 > 1 > 1-4

Background We investigated choroidal thicknesses at five sites in two siblings (four eyes) with nanophthalmos using swept-source optical coherence tomography. Case presentation Case 1, a 51-year-old Japanese female with high hyperopia (Right: +20.5 Dioptors, Left: +19.5 Dioptors), had axial lengths of 15.6 mm in both eyes. Case 2, a 55-year-old Japanese male with high hyperopia (Right: +22.5 Dioptors,...

article

Intravitreal Tissue Plasminogen Activator, Ranibizumab, and Gas Injection for Submacular Hemorrhage in Polypoidal Choroidal Vasculopathy

Yorihisa Kitagawa, Hiroyuki Shimada, Ryusaburo Mori, Kouji Tanaka, more

Ophthalmology > 2016 > 123 > 6 > 1278-1286

To investigate the efficacy of intravitreal injection of recombinant tissue plasminogen activator (rt-PA), ranibizumab, and gas without vitrectomy for submacular hemorrhage.Prospective, interventional, consecutive case series.Twenty consecutive patients (20 eyes) with submacular hemorrhage secondary to exudative age-related macular degeneration (AMD) or polypoidal choroidal vasculopathy (PCV).Ranibizumab,...

article

One-Year Outcomes with Half-Dose Verteporfin Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Kyoko Fujita, Yutaka Imamura, Kei Shinoda, Celso Soiti Matsumoto, more

Ophthalmology > 2015 > 122 > 3 > 555-561

To assess the 1-year outcome of half-dose verteporfin photodynamic therapy (PDT) for patients with chronic central serous chorioretinopathy (CSC).Retrospective, interventional case series with no controls.A total of 204 eyes of 204 patients with chronic CSC were studied.Fluorescein angiography (FA) and indocyanine green angiography (ICGA) were performed before PDT. The best-corrected visual acuities...

article

Data from Phase 3 Studies in Wet Age-Related Macular Degeneration

Mitsuko Yuzawa, Kyoko Fujita, Kim U. Wittrup-Jensen, Christiane Norenberg, more

Ophthalmology > 2015 > 122 > 3 > 571-578

To evaluate the effect of intravitreal aflibercept injection on visual function in wet age-related macular degeneration (AMD).Prospective, multicenter, double-masked, active-controlled, parallel-group, randomized phase 3 clinical studies (VEGF Trap-Eye: Investigation of Efficacy and Safety in Wet AMD [VIEW] 1 and 2 [clinicaltrials.gov identifiers, NCT00509795 and NCT00637377, respectively]).Patients...

article

ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration

Souska Zandi, Shintaro Nakao, Kwang-Hoon Chun, Paolo Fiorina, more

Cell Reports > 2015 > 10 > 7 > 1173-1186

Age is a major risk factor in age-related macular degeneration (AMD), but the underlying cause is unknown. We find increased Rho-associated kinase (ROCK) signaling and M2 characteristics in eyes of aged mice, revealing immune changes in aging. ROCK isoforms determine macrophage polarization into M1 and M2 subtypes. M2-like macrophages accumulated in AMD, but not in normal eyes, suggesting that these...

article

Retinal pigment epithelial detachment associated with retinal pigment epithelium thinning revealed by optical coherence tomography

Satoko Notani, Ryusaburo Mori, Mitsuko Yuzawa, Akiyuki Kawamura

Japanese Journal of Ophthalmology > 2015 > 59 > 5 > 305-311

Purpose To clarify the characteristics and outcomes of unusual retinal pigment epithelial detachments (PEDs). These PEDs had one or several sites of apparent thinning of the RPE, or no RPE at all, as shown on optical coherence tomography (OCT). Methods Eight cases with PEDs showed apparent thinning of the RPE in the roof of the PED at one or more sites on OCT. Color fundus photographs, fundus examination...

article

Intravitreal Aflibercept for Macular Edema Secondary to Central Retinal Vein Occlusion: 18-Month Results of the Phase 3 GALILEO Study

Mark Gillies, Jennifer Arnold, Ian McAllister, Simon Chen, more

American Journal of Ophthalmology > 2014 > 158 > 5 > 1032-1038.e2

article

Prophylaxis for acute scleral buckle infection using 0.25 % povidone-iodine ocular surface irrigation during surgery

Hiroyuki Shimada, Hiroyuki Nakashizuka, Takayuki Hattori, Kyuen Otani, more

International Ophthalmology > 2014 > 34 > 2 > 211-216

To investigate whether repeated washing of the ocular surface with 0.25 % povidone-iodine during scleral buckling surgery minimizes ocular surface bacterial contamination at completion of the procedure. A total of 489 consecutive eyes that underwent scleral buckling at a single institution were categorized into two groups according to the intraoperative ocular surface washing method used during two...

article

Indocyanine green angiographic and optical coherence tomographic findings support classification of polypoidal choroidal vasculopathy into two types

Akiyuki Kawamura, Mitsuko Yuzawa, Ryusaburo Mori, Miho Haruyama, more

Acta Ophthalmologica > 91 > 6 > e474 - e481

Purpose: We assessed the characteristic indocyanine green angiographic (ICGA) and spectral domain optical coherence tomographic (SD‐OCT) findings of two types of polypoidal choroidal vasculopathy (PCV), distinguishable by different filling patterns on ICGA. Methods: Thirty‐one eyes with PCV were classified into types 1 and 2 based on ICGA findings of either the presence or absence of both a feeder...

article

Low luminance visual acuity in patients with central serous chorioretinopathy

Kyoko Fujita, Kei Shinoda, Celso Soiti Matsumoto, Yutaka Imamura, more

Clinical and Experimental Optometry > 96 > 1 > 100 - 105

BackgroundThe aim was to determine the low luminance visual acuity in eyes with central serous chorioretinopathy. MethodsSeven eyes of seven patients with central serous chorioretinopathy and six eyes of six age‐matched normal volunteers were examined. Low luminance visual acuity charts were created by an Apple Power Mac G5 computer and displayed on a cathode ray tube monitor (SONY GDM‐F500). The...

article

Treatment results at 1 year of ranibizumab therapy for polypoidal choroidal vasculopathy in eyes with good visual acuity

Ryusaburo Mori, Mitsuko Yuzawa, Eriko Akaza, Miho Haruyama

Japanese Journal of Ophthalmology > 2013 > 57 > 4 > 365-371

Purpose To evaluate the efficacy of intravitreal ranibizumab (IVR) for subfoveal polypoidal choroidal vasculopathy (PCV) in eyes with a best corrected visual acuity (BCVA) of 0.6 (logMAR 0.22) or better. Methods Fifty eyes with BCVA between 0.6 (logMAR 0.22) and 1.0 (logMAR 0) and subfoveal PCV were treated with IVR for 3 consecutive months. Additional IVR was given at subsequent monthly visits,...

article

Reducing bacterial contamination inside fluid catch bag in 25-gauge vitrectomy by use of 0.25 % povidone-iodine ocular surface irrigation

Hiroyuki Shimada, Hiroyuki Nakashizuka, Takayuki Hattori, Yorihisa Kitagawa, more

International Ophthalmology > 2013 > 33 > 1 > 35-38

To examine the bacterial detection rate in infusion fluid collected inside the fluid catch bag during 25-gauge (25G) vitrectomy when the ocular surface was irrigated with infusion fluid or 0.25 % povidone-iodine. Two groups using different fluids for ocular surface irrigation during 25G vitrectomy were studied. Fifty-five consecutive eyes received ocular surface irrigation with infusion fluid (IF...

article

Minimizing the endophthalmitis rate following intravitreal injections using 0.25 % povidone–iodine irrigation and surgical mask

Hiroyuki Shimada, Takayuki Hattori, Ryusaburo Mori, Hiroyuki Nakashizuka, more

Graefe's Archive for Clinical and Experimental Ophthalmology > 2013 > 251 > 8 > 1885-1890

Background To examine the efficacy of complying with an infection control manual for intravitreal injection of anti-vascular endothelial growth factor (VEGF) preparations in reducing the rate of endophthalmitis. Methods We retrospectively reviewed intravitreal anti-VEGF injections conducted by vitreoretinal specialists at the outpatient injection room of a single university hospital between July...

article

Reading performance with different contrast characters in patients with central serous chorioretinopathy

Kyoko Fujita, Celso Soiti Matsumoto, Yoshihiro Mizutani, Yutaka Imamura, more

Acta Ophthalmologica > 90 > 7 > e575 - e577

article

Correlation of Integrity of Cone Outer Segment Tips Line With Retinal Sensitivity After Half-dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Kyoko Fujita, Kei Shinoda, Yutaka Imamura, Celso Soiti Matsumoto, more

American Journal of Ophthalmology > 2012 > 154 > 3 > 579-585

To investigate the relationship between the integrity of the photoreceptor microstructures and retinal sensitivity after half-dose photodynamic therapy (PDT) in eyes with chronic central serous chorioretinopathy (CSC). Prospective, noncomparative, interventional case series. Thirteen eyes of 13 patients with chronic CSC who had received half-dose verteporfin PDT were studied. The best-corrected...

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Search results for: Mitsuko Yuzawa

Baseline data from a multicenter, 5-year, prospective cohort study of Japanese age-related macular degeneration: an AMD2000 report

A 5-year multicenter prospective cohort study on the long-term visual prognosis and predictive factors for visual outcome in Japanese patients with age-related macular degeneration: the AMD2000 study

Wet laboratory training using porcine eyes with eyelids

Reduced anterior chamber contamination by frequent surface irrigation with diluted iodine solutions during cataract surgery

Postoperative roll cake-like macular fold after retinal detachment surgery

Choroidal thickness findings in two siblings with nanophthalmos by swept source-OCT: a case report

Intravitreal Tissue Plasminogen Activator, Ranibizumab, and Gas Injection for Submacular Hemorrhage in Polypoidal Choroidal Vasculopathy

One-Year Outcomes with Half-Dose Verteporfin Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

Data from Phase 3 Studies in Wet Age-Related Macular Degeneration

ROCK-Isoform-Specific Polarization of Macrophages Associated with Age-Related Macular Degeneration

Retinal pigment epithelial detachment associated with retinal pigment epithelium thinning revealed by optical coherence tomography

Intravitreal Aflibercept for Macular Edema Secondary to Central Retinal Vein Occlusion: 18-Month Results of the Phase 3 GALILEO Study

Prophylaxis for acute scleral buckle infection using 0.25 % povidone-iodine ocular surface irrigation during surgery

Indocyanine green angiographic and optical coherence tomographic findings support classification of polypoidal choroidal vasculopathy into two types

Low luminance visual acuity in patients with central serous chorioretinopathy

Treatment results at 1 year of ranibizumab therapy for polypoidal choroidal vasculopathy in eyes with good visual acuity

Reducing bacterial contamination inside fluid catch bag in 25-gauge vitrectomy by use of 0.25 % povidone-iodine ocular surface irrigation

Minimizing the endophthalmitis rate following intravitreal injections using 0.25 % povidone–iodine irrigation and surgical mask

Reading performance with different contrast characters in patients with central serous chorioretinopathy

Correlation of Integrity of Cone Outer Segment Tips Line With Retinal Sensitivity After Half-dose Photodynamic Therapy for Chronic Central Serous Chorioretinopathy

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