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The advent of new chronic hepatitis C virus (HCV) therapies requires characterization of patients in order to predict adequate treatment. A good candidate marker is Programmed Cell Death-1 (PD-1) which is involved in progression of HCV infection. The aim of this study was to analyse the effect of several single nucleotide polymorphisms of PD-1 gene and several previously associated factors (IL28B...
To investigate the effect of sustained virological response (SVR) on impaired fasting glucose (IFG) and/or type 2 diabetes (T2DM); to assess the influence of glucose abnormalities on the SVR rate.1059 patients with chronic HCV; normal glucose (< 100mg/dl) in 734, IFG (between 100 and 125mg/dl) in 218, and T2DM (⩾126mg/dl) in 107 cases, were treated with interferon plus ribavirin over 24 or 48 weeks,...
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