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Porous salmon calcitonin (sCT)-loaded PLGA microspheres (size range 35-140 μm) of varying matrix characteristics were prepared by an aqueous emulsification process using either a temperature gradient (Tmp) or dilution (Dil) of the continuous phase (CP). The Tmp technique resulted in microspheres with a hollow internal core and a porous wall. The core size and thickness of the porous wall were dependent...
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