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Systemic sclerosis (SSc) is a multi-organ connective tissue disease characterized by immune dysregulation and organ fibrosis. Severe organ involvement, especially of the skin and lung, is the cause of morbidity and mortality in SSc. Interstitial lung disease (ILD) includes multiple lung disorders in which the lung tissue is fibrotic and stiffened. The purpose of this study was to translate ultrasound...
We have developed a noninvasive lung ultrasound surface wave elastography (LUSWE) technique for measuring superficial lung tissue stiffness. The purpose of this paper was to demonstrate the clinical use of LUSWE for assessing patients with interstitial lung disease (ILD). In LUSWE, a local 0.1s harmonic vibration is generated on the chest wall of a subject using a handheld vibrator. An ultrasound...
A lung ultrasound surface wave elastography (LUSWE) technique is developed to measure superficial lung tissue elastic properties. A small, local, and short 0.1 second harmonic vibration is generated by the indenter of a handheld shaker on the skin of a subject. The ultrasound probe is positioned about 5 mm away from the indenter in the same intercostal space to measure the generated surface wave propagation...
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