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Aim
To select an optimal whole‐genome amplification (WGA) method to improve the efficiency of the preimplantation genetic diagnosis and screening (PGD/PGS) of beta‐thalassaemia disorders.
Methods
Fifty‐seven fibroblast samples with defined beta‐thalassaemia variations and forty‐eight single‐blastomere samples were amplified from single‐, two‐, and five‐cell samples by multiple annealing and looping‐based...
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