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Despite its well‐defined role as a serum growth factor during fetal liver development and hepatic oncogenesis, the biological significance of cytoplasmic alpha‐fetoprotein (AFP) remains incompletely understood. Here, we provide evidence to illustrate that cytoplasmic AFP may function as a regulator in the phosphatidylinositol 3‐kinase (PI3K)/AKT pathway in human hepatocellular carcinoma cells. The...
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