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The ongoing search for better antibacterial wound care dressings has led to the design and fabrication of advanced functional nanomaterials. Taking advantage of electrospinning and cold atmospheric plasma (CAP), free-standing nanofibrous scaffolds are promising for use in novel biomedical applications. Random and aligned polyvinyl alcohol (PVA)/polyacrylic acid (PAA) nanofiber scaffolds are fabricated...
Electrospinning is a bio-fabrication method, which helps to produce highly interconnected nano-porous structure with a high surface to volume ratio by using polymer solutions. In tissue engineering applications, scaffolds composed of electrospun nanofibers are produced from synthetic polymers to resemble specific tissue. Most of synthetic polymers has high hydrophobicity since the nonpolar groups...
Vascular scaffolds produced by bio-fabrication methods can provide ideal conditions for attachment and proliferation of ECs (endothelial cells). But these grafts might not allow migration of cells into the scaffold. Therefore, scaffolds, which resembles ECMs (extracellular matrix) should produce by changing scaffold size and shape. The diameter of nanofibers can be controlled by using electrospinning...
In the scope of bone tissue engineering, there has still been great amount of demand on designing biomimetic scaffolds that induces differentiation of osteoprogenitor cells by cell-matrix interaction at the nanoscale as well as mimicking micro assembly of compact bone while providing high mechanical strength. In this study, in order to use in the treatment of large bone defects, osteon mimetic 3D...
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