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In the scope of bone tissue engineering, there has still been great amount of demand on designing biomimetic scaffolds that induces differentiation of osteoprogenitor cells by cell-matrix interaction at the nanoscale as well as mimicking micro assembly of compact bone while providing high mechanical strength. In this study, in order to use in the treatment of large bone defects, osteon mimetic 3D...
Clinic applications of bone tissue (BT) transplantation are used widely for treatment of large bone defects. In BT field, development of biomimetic bone tissue scaffolds which have appropriate chemical and mechanical properties for clinic applications is needed. Biomimetic bone tissue scaffolds should be used for bone grafts which are developed with tissue engineering approach to mimic extracellular...
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