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Paired-like homeodomain transcription factor 2 (PITX2) has been implicated as one of the genes responsible for Rieger syndrome. It has been also shown to play a central role during development. In this study, we investigated the functional role of PITX2 in keratinocyte differentiation. RT–PCR analysis showed that PITX2c isoform was predominantly expressed in a differentiation-dependent manner. Consistent...
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