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This paper describes the development of physically-modified chitosan nanosponges to probe cellular behaviors and molecular-level structural responses of MDA-MB-231 cells (human breast cancer cells) adhered onto these modified nanosponges. After 4 and 12 hours culture, MDA-MB-231 cells were investigated to decipher the cellular responses on these chitosan nanosponges through using scanning electron...
Developing artificial scaffolding structures in vitro in order to mimic physiological-relevant situations in vivo is critical in many biological and medical arenas including bone and cartilage generation, biomaterials, small-scale biomedical devices, tissue engineering, as well as the development of nanofabrication methods. We focus on using simple physical principles (photolithography) and chemical...
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