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Hereditary spastic paraplegia (HSP) designates a group of genetic disorders typically leading to spasticity in the lower limbs and consequently to gait disorders. Although the symptoms are similar to those of cerebral palsy (CP), the correct diagnosis is important for treatment recommendations as one condition is progressive in nature whereas the other is not. Due to the heterogeneity of HSP, genetic...
A methodological modular framework is presented for automated assessment of gait patterns. The processing steps of data selection, gait parameter calculation and evaluation are not limited to a specific field of application and are largely independent of case-based clinical expert knowledge. For these steps, a variety of mathematical methods was used and the validity of the approach to assess gait...
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