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The atomic force microscope (AFM) has been widely used to manipulate nanoparticles, nanowires, and nanotubes for applications such as nanostructure building, nanocharacterization, and biomanipulation. However, conventional AFM-based nanomanipulation is inefficient because of the serial scan–manipulation–scan process involved. In this paper, high-efficiency automated nanomanipulation with a parallel...
We present a novel force sensor for cell indentation and cell injection. This force sensor is a monolithic structure that integrates two resonators. It provides a surface sensitive to out-of-plane forces where a living cell can be conveniently placed for manipulation. Normal forces applied upon the cell under study are estimated via frequency shifts of the resonators. In this paper, we develop a theoretical...
We present a novel force sensor for the injection of both suspended and adherent cells. Unlike most configurations, this force sensor is independent of the tool interacting with the cells. It is a planar structure that provides a surface sensitive to out-of-plane forces where living cells can be placed for manipulation. It also integrates two beam resonators. Forces perpendicular to the sensor's plane...
This paper deals with the design of a micro-force sensing device for biomechanical characterization of biological samples. This device combines (SPM) techniques and advanced robotics approaches and allows to carry out in vitro prolonged observations as well as biomechanical characterization experiments. Elastic properties of biological samples are reflected to the macroscale during the mechanical...
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