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Terahertz (THz) spectral properties of human cornea are explored as a function of central corneal thickness (CCT) and corneal water content, and the clinical utility of THz-based corneal water content sensing is discussed. Three candidate corneal tissue water content (CTWC) perturbations, based on corneal physiology, are investigated that affect the axial water distribution and total thickness. The...
THz medical imaging has made significant advances in the years since the first results were published in the late 1990s. The field has benefited significantly from advances in source/detector technology, room temperature component operation, and extensive spectroscopic studies of the THz properties of tissue. Additionally, clinical translation of THz medical imaging technology has been aided by the...
Variations in water volume fraction have been investigated as a possible source of contrast in several reflective THz medical imaging applications including corneal hydration sensing and burn wound severity diagnosis. Due to surface roughness and non-planar geometry most reflective systems employ low loss windows such as quartz or sapphire to minimize the effects of the specimen's topology. This creates...
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