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In rodents, pyramidal cell firing patterns from waking may be replayed in nonrapid eye movement sleep (NREM) sleep during hippocampal sharp wave ripples (HC‐SWR). In humans, HC‐SWR have only been recorded with electrodes implanted to localize epileptogenicity. Here, we characterize human HC‐SWR with rigorous rejection of epileptiform activity, requiring multiple oscillations and coordinated sharp...
This article addresses the problem of real-time seizure detection from intracranial EEG (IEEG). One difficulty in creating an approach that can be used for many patients is the heterogeneity of seizure IEEG patterns across different patients and even within a patient. In addition, simultaneously maximizing sensitivity and minimizing latency and false detection rates has been challenging as these are...
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