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Acoustic property of tissue such as speed of sound (SoS), attenuation provide beneficial information for the pathological diagnosis. The pathological change due to liver fibrosis have been investigated by using a 250-MHz central frequency transducer with fine spatial resolution of 4-µm. The SoS and attenuation of rat liver in case of control and fibrosis models were measured by bioacoustics microscopy...
Ultrasound imaging is ideally suited for early-stage assessments of liver steatosis and fibrosis, but conventional ultrasound B-mode images do not display quantitative tissue information because conventional ultrasound formation does not incorporate modeling of the complex interactions between ultrasound and liver tissue in normal and diseased states. In this study, two normal, two fatty, and two...
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