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Caffeine is one of the most widely used psychostimulants in the world and possesses central excitative, anti‐depressive, and neuroprotective properties. However, excessive ingestion or abuse of caffeine can lead to intoxication. Many toxic effects are attributed to oxidative damage, and nuclear factor erythroid 2‐related factor 2 (Nrf2) is a critical intracellular regulator of the oxidative stress...
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