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Dynamic changes in metabolites may affect liver disease progression, and provide new methods for predicting liver damage. We used ultra‐performance liquid chromatography–mass spectroscopy to assess serum metabolites in healthy controls (HC), and patients with acute hepatitis E (AHE) or hepatitis E virus acute liver failure (HEV‐ALF). The principal component analysis, partial least squares discriminant...
Fulminant hepatitis E may lead to acute liver failure (ALF). Perturbations of intestinal microbiota are related to severe liver disease. To study the correlations between faecal microbiota and the occurrence and exacerbation of hepatitis E virus (HEV) infection, we characterized 24 faecal samples from 12 patients with acute hepatitis E (AHE) and 12 patients with HEV‐ALF using high‐throughput sequencing...
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