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A novel biodegradable sodium poly(aspartic acid) (PASP) hydrogel with microporous structure was manufactured using electrospun polysuccinimide (PSI) nanofibers. PSI is the intermediate of sodium PASP and could be electospun into nanofibers easily. Firstly, PSI nanofibers were prepared from PSI/N, N-dimethylformamide solution. Then the PSI nanofibrous mats were crosslinked and hydrolyzed to obtain...
Stable pH-sensitive poly(aspartic acid) (PASP) hydrogel in nanofibrous structure was successfully manufactured. Firstly, polysuccinimide (PSI), the intermediate of PASP, was synthesized by thermal polymerization of aspartic acid and electrospun into nanofibrous mat. Secondly, imide rings on the main chains of PSI were partly opened to form crosslinking points by amino groups of ethylenediamine. Eventually,...
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