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A new concept and devices for autonomous switching of valves and pumps in microfabricated flow channels are proposed. An electrowetting-based valve consisting of gold and zinc opened when an electrolyte solution reached the zinc part in a controlling flow channel and a mixed potential was applied to the gold valve electrode. Clock circuits that open the valves at predetermined times and logic circuits...
A new concept and devices for autonomous switching of valves and pumps in microfabricated flow channels are proposed. An electrowetting-based valve formed with a gold electrode was opened when an electrolyte solution reached a zinc electrode in a controlling flow channel. Following this, a H2O2 solution was introduced into a diaphragm micropump with manganese dioxide (MnO2) powder. Oxygen bubbles...
As a trial to realize an automatic microfluidic system, functions such as automatic valve operation, adjustment of mixing time, pH-regulation, and sensing were integrated on a chip. Microfluidic transport was achieved by capillary action. The transport and merge of solutions was controlled by gold working electrodes that functioned as valves. The mixing valve was also used as a delay line to take...
In conducting a bio/chemical analysis on a chip, several different procedures are usually required. In this study, we demonstrate the possibility to conduct necessary procedures on a single chip. Our fabricated device has functions such as automatic mixing of solutions, pH-regulation, and detection based on electrochemiluminescence (ECL). A reagent solution containing Ru(bpy)32+ and a sample solution...
An integrated device which can conduct timely transport of a sample solution and analyze its components was constructed. The transport of solutions was based on capillary action on hydrophilic glass areas and the control by valves which operate based on electrowetting. Electrochemical sensors including glucose, lactate, GOT, GPT, pH, ammonia, urea, and creatinine were integrated. Sensors for the former...
Electrowetting was used to fabricate an integrated highly efficient microfluidic transport system. As an option, a row of elongated gold working electrodes were used to generate a driving force to mobilize a solution in a flow channel. Flow velocity could be changed by changing the potential of the working electrode. The solutions could be transported to any desired direction without using any valves...
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