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Two types of neamine derivatives, neamine-dinucleotide conjugates 8a–g and neamine-PNA conjugates 12a–c and 14a–d, were synthesized. Compound 8a–g were synthesized by the condensation of azido-neamine with dinucleotide-5′-carboxylic acids, followed by reduction and deprotection. Compound 12a–c and 14a–d were synthesized by the similar strategy. The binding affinities of conjugates 8a–g, 12a–c, and...
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