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Efficient delivery of genes and therapeutic agents to the interior of the cell is critical for modern biotechnology. Herein, a new type of chemical‐free cell poration method—hypersonic poration—is developed to improve the cellular uptake, especially the nucleus uptake. The hypersound (≈GHz) is generated by a designed piezoelectric nano‐electromechanical resonator, which directly induces normal/shear...
In article number 1602962, Xuexin Duan and co‐workers, explore a novel chemical‐free cell poration method – “hypersonic poration”, which is developed to improve the cellular uptake, especially nucleus uptake, using a designed piezoelectric nanoelectromechanical resonator. The hypersound has a typical frequency larger than GHz, which can directly interact with the cell membrane and create reversible...
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