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The Smith-Waterman algorithm, which produces the optimal local alignment between pairwise sequences, is universally used as a key component in bioinformatics fields. It is more sensitive than heuristic approaches, but also more time-consuming. To speed up the algorithm, Single-Instruction Multiple-Data (SIMD) instructions have been used to parallelize the algorithm by leveraging data parallel strategy...
Sequence alignment algorithms are a basic and critical component of many bioinformatics fields. With rapid development of sequencing technology, the fast growing reference database volumes and longer length of query sequence become new challenges for sequence alignment. However, the algorithms have prohibitively high time and space complexity. In this paper, we present DSA, a scalable distributed...
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