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Paclitaxel-loaded chitosan oligosaccharide (CSO) nanoparticles were prepared by interfacial polyaddition between amino group of CSO and epoxy group of ethylene glycol diglycidyl ether (EGDE) in an O/W miniemulsion system. Using Span 85 and Tween 20 as the surfactants of oil phase and water phase, respectively, the stable O/W miniemulsion with about 200nm droplet size could be obtained. When the molar...
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