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A fiber surface plasmon resonance (SPR) sensor with roughened gold film and curve graphene coating for glucose monitoring with enhanced sensitivity is proposed in the paper. This is the first attempt to employ ultrasonic cavitation to roughen the gold layer on micron-scale cylindrical surface, which could construct nanostructures on the surface of gold layer to stimulate local surface plasmon resonance...
A novel surface plasmon resonance (SPR) sensor bound to the borate polymer PAA-ran-PAAPBA through a layer-by-layer method was proposed for the determination of glucose concentration. In contrast to the enzyme electrode sensor, the use of optical refractive index sensing to detect glucose concentration eliminates the measurement drift caused by bioelectricity when the sensor is implanted into subcutaneous...
Measuring the glucose concentration of interstitial fluid in human body is an effectively way to control and treat diabetes. A surface plasmon resonance (SPR) system based on a miniature integrated SPR sensor is presented in this paper to measure the glucose concentration in interstitial fluid. D-galactose/D-glucose Binding Protein (GGBP) which can specifically absorb glucose is immobilized onto the...
A novel minimally invasive way to measure blood glucose concentration is proposed by combining interstitial fluid (ISF) transdermal extraction and surface plasmon resonance (SPR) detection. 55 kHz low-frequency ultrasound pulses are applied for 30 seconds to enhance the skin permeability and then interstitial fluid is extracted out of skin by vacuum. The glucose concentration in the interstitial fluid...
A novel minimally invasive way to measure the diabetic's real-time blood glucose concentration in vitro is proposed by combining interstitial fluid transdermal extraction ultrasonically and surface plasma resonance detecting. Low-frequency ultrasound is employed to enhance the skin permeability to interstitial fluid by disrupting the stratum corneum lipid bilayers and then interstitial fluid is extracted...
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