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Dr. R.K. Gherardi presented two papers at the symposium, detailing his researches into a proposed new clinical entity which he has entitled Macrophagic Myofasciitis (MMF). In his first paper he described the histopathologic and immunologic characteristics of the condition, and in the second, the clinical and serologic features. Dr. Gherardi believes that MMF, a syndrome of ascending myalgias, fatigue...
Background: Activation of hepatic stellate cells is the earliest step in fibrogenesis. Alpha-smooth muscle actin (α-SMA), expressed by activated hepatic stellate cells, and C-terminal procollagen α1(III) propeptide (PIIICP) are early markers of fibrogenesis and should precede fibrosis.Aim: Determine if suppression of hepatitis B virus replication with lamivudine would decrease fibrogenesis as measured...
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