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Purpose
Carbon‐13 (13C) MR spectroscopy (MRS) of the human brain at 7 Tesla (T) may pose patient safety issues due to high radiofrequency (RF) power deposition for proton decoupling. The purpose of present work is to study the feasibility of in vivo 13C MRS of human brain at 7 T using broadband low RF power proton decoupling.
Methods
Carboxylic/amide 13C MRS of human brain by broadband stochastic...
Previously, we devised a novel strategy for in vivo13C MRS using [2‐13C]glucose infusion and low‐power proton decoupling, and proposed that this strategy could be used to acquire 13C MR spectra from the frontal lobe of the human brain. Here, we demonstrate, for the first time, in vivo13C MRS of human frontal lobe acquired at 3 T. Because the primary metabolites of [2‐13C]glucose can be decoupled using...
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