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The impact of spinal cord injury (SCI) on potential functional reorganization in neuronal populations in motor cortical areas remains unknown, though its influence on functional recovery may be significant. The cortical neuronal data was recorded from a monkey while it was trained to walk bipedally on a treadmill both before and after spinal cord injury. By using the correlation coefficients between...
In this work, we took the analysis of neural interaction based on the data recorded from the motor cortex of a monkey, when it was trained to complete multi-targets reach-to-grasp tasks. As a recently proved effective tool, Dynamic Bayesian Network (DBN) was applied to model and infer interactions of dependence between neurons. In the results, the gained networks of neural interactions, which correspond...
In this work, we recorded the spike train data from a rhesus monkey's motor cortex while it was trained to perform reach-to-grasp task at different directions and orientations. The neurons were divided into several classes according to their neuronal activities, and each class of neuron encoded a kind of functional parameter, such as direction-related, orientation-related and so on. Then we applied...
The relationship between movement kinematics and motor cortical activity was studied in monkeys performing a center-out reaching task during their adaptation to force perturbations applied to the wrist. The main feature of adaptive changes in movement kinematics was anticipatory deviation of hand paths in the direction opposite to that of the upcoming perturbation. We identified a group of neurons...
We have developed a method for training animals to control artificial devices from cortical signals. In this report we describe a series of experiments designed to parameterize a cortical control algorithm without an animal having to move its arm. Instead, a highly motivated animal observes as the computer drives a cursor move towards a set of targets once each in a center-out task. From the neuronal...
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