The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
The urticaria activity score (UAS) is the gold standard for assessing disease activity in patients with chronic spontaneous urticaria (CSU). Two different versions, the UAS7 and UAS7TD, are currently used in clinical trials and routine care. To compare both versions and to obtain data on their interpretability, 130 CSU patients applied both versions and globally rated their disease activity as none,...
Background
Atopic dermatitis (AD) is a common skin disorder. Its diagnosis relies on clinical judgment. Mild and untypical manifestations may cause diagnostic difficulties. Biomarkers for the differential diagnostic workup of AD are needed.
Objective
To test whether the results of skin provocation with cowhage, an established model of histamine‐independent pruritus, and histamine are different...
BackgroundThe most intriguing function attributed to interleukin‐31 (IL‐31) is its ability to induce pruritus in pathologic conditions, such as atopic dermatitis (AD). As of today, this feature of IL‐31 was tested in vivo only in animal models.
MethodsTen patients with AD and 10 healthy controls were challenged with IL‐31 and NaCl (negative control) by skin prick testing. Twenty additional healthy...
Background Sodium cromoglicate (SCG) has long been used in the management of allergic diseases, including as an ointment for atopic dermatitis. Although mast cell stabilization was initially considered as its mechanism of action, anti‐inflammatory actions and modulation of sensory nerve function have also been suggested.
Objectives To investigate the mechanism(s) by which SCG relieves allergen‐...
Hintergrund Die kausale Behandlung von chronischem Pruritus ist nicht immer möglich oder zeigt nicht den gewünschten Erfolg, sodass auf eine symptomatische Therapie ausgewichen werden muss. Zugelassen sind dazu nur Antihistaminika, die in niedriger Dosierung meist nicht antipruritisch wirksam sind. Ziel dieser Arbeit war es, anhand einer retrospektiven Fallserienanalyse den antipruritischen Effekt...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.